BESS FROST, Ph.D.

Bess Frost is Salame-Feraud Director of the Center for Alzheimer's Disease Research and Professor of Molecular Biology, Cell Biology and Biochemistry at Brown University. Her research revolves around the basic neurobiology connecting toxic forms of tau to neuronal death and dysfunction. The Frost laboratory has discovered that the detrimental effects of pathogenic tau on nuclear and genomic architecture activate retrotransposons and alter RNA metabolism. Through this work, they have identified multiple new targets for therapeutic development, as well as compounds that interfere with these processes and suppress tau-induced neurotoxicity.